BDBM272157 (S)-1-Benzyl-5-(3-fluoro-2-methylphenyl)-N-hydroxy- 1,4,5,6-tetrahydrocyclopenta[c]pyrazole-5- carboxamide::US10065948, 92::US10457675, Example 92

SMILES: Cc1c(F)cccc1[C@@]1(Cc2cnn(Cc3ccccc3)c2C1)C(=O)NO

InChI Key: InChIKey=FLMXRQPTJQVIKH-NRFANRHFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272157 ((S)-1-Benzyl-5-(3-fluoro-2-methylphenyl)-N-hydroxy...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(Cc3ccccc3)c2C1)C(=O)NO |r| Show InChI InChI=1S/C21H20FN3O2/c1-14-17(8-5-9-18(14)22)21(20(26)24-27)10-16-12-23-25(19(16)11-21)13-15-6-3-2-4-7-15/h2-9,12,27H,10-11,13H2,1H3,(H,24,26)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272157 ((S)-1-Benzyl-5-(3-fluoro-2-methylphenyl)-N-hydroxy...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(Cc3ccccc3)c2C1)C(=O)NO |r| Show InChI InChI=1S/C21H20FN3O2/c1-14-17(8-5-9-18(14)22)21(20(26)24-27)10-16-12-23-25(19(16)11-21)13-15-6-3-2-4-7-15/h2-9,12,27H,10-11,13H2,1H3,(H,24,26)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair