BDBM27231 ARC-1003, 4::[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(3-carbamoylpropyl)carbamate

SMILES: NC(=O)CCCNC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key: InChIKey=FJRSRRVNGVLITF-FRJWGUMJSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Mus musculus (mouse))	BDBM27231 (ARC-1003, 4 | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9...) Show SMILES NC(=O)CCCNC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C15H21N7O6/c16-8(23)2-1-3-18-15(26)27-4-7-10(24)11(25)14(28-7)22-6-21-9-12(17)19-5-20-13(9)22/h5-7,10-11,14,24-25H,1-4H2,(H2,16,23)(H,18,26)(H2,17,19,20)/t7-,10-,11-,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.87E+4	n/a	n/a	n/a	7.5	30
Institute of Chemistry in Estonia					Assay Description The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...				J Med Chem 52: 308-21 (2009) Article DOI: 10.1021/jm800797n BindingDB Entry DOI: 10.7270/Q2RX99FQ
					More data for this Ligand-Target Pair