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SMILES: COCc1nc2sc(nc2c(=O)n1C1CCOCC1)N1CCC[C@@H]1C(=O)NCc1ccccc1

InChI Key: InChIKey=NMASISFVUMRETE-GOSISDBHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273145   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))		BDBM273145
PNG
((R)-N-benzyl-1-[5-methoxymethyl-7-oxo-6-(tetrahydr...)
Show SMILES COCc1nc2sc(nc2c(=O)n1C1CCOCC1)N1CCC[C@@H]1C(=O)NCc1ccccc1 |r|
Show InChI InChI=1S/C24H29N5O4S/c1-32-15-19-26-22-20(23(31)29(19)17-9-12-33-13-10-17)27-24(34-22)28-11-5-8-18(28)21(30)25-14-16-6-3-2-4-7-16/h2-4,6-7,17-18H,5,8-15H2,1H3,(H,25,30)/t18-/m1/s1
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US Patent
n/an/a 10n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...

US Patent US10065972 (2018)


BindingDB Entry DOI: 10.7270/Q23X88P5
More data for this
Ligand-Target Pair