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SMILES: Cn1ccn2c1nc1sc(nc1c2=O)N1CCC[C@@H]1C(=O)NCc1ccccc1

InChI Key: InChIKey=KDOWGKJXZRAHCN-CQSZACIVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273157   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))		BDBM273157
PNG
((R)-N-benzyl-1-(5-methyl-9-oxo-5,9-dihydroimidazo[...)
Show SMILES Cn1ccn2c1nc1sc(nc1c2=O)N1CCC[C@@H]1C(=O)NCc1ccccc1 |r|
Show InChI InChI=1S/C20H20N6O2S/c1-24-10-11-26-18(28)15-17(23-19(24)26)29-20(22-15)25-9-5-8-14(25)16(27)21-12-13-6-3-2-4-7-13/h2-4,6-7,10-11,14H,5,8-9,12H2,1H3,(H,21,27)/t14-/m1/s1
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PC cid
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US Patent
n/an/a 4.90n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...

US Patent US10065972 (2018)


BindingDB Entry DOI: 10.7270/Q23X88P5
More data for this
Ligand-Target Pair