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BDBM27366 2-(2-aminopyrimidin-4-yl)-7-methyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::Pyrrolopyridinone, 85

SMILES: CC1CNC(=O)c2cc([nH]c12)-c1ccnc(N)n1

InChI Key: InChIKey=UXWFMSAYLCYBST-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27366   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cdc7 Kinase


(Homo sapiens (Human))
BDBM27366
PNG
(2-(2-aminopyrimidin-4-yl)-7-methyl-1H,4H,5H,6H,7H-...)
Show SMILES CC1CNC(=O)c2cc([nH]c12)-c1ccnc(N)n1
Show InChI InChI=1S/C12H13N5O/c1-6-5-15-11(18)7-4-9(16-10(6)7)8-2-3-14-12(13)17-8/h2-4,6,16H,5H2,1H3,(H,15,18)(H2,13,14,17)
PDB

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UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6n/an/an/an/a7.925



Nerviano Medical Sciences Srl



Assay Description
The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...


J Med Chem 52: 293-307 (2009)


Article DOI: 10.1021/jm800977q
BindingDB Entry DOI: 10.7270/Q27W69JX
More data for this
Ligand-Target Pair