BDBM27392 3-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::pyrrolopyridinone scaffold, 14

SMILES: Nc1nccc(n1)-c1c[nH]c2CCNC(=O)c12

InChI Key: InChIKey=FXIGVWLQKAWHES-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27392 (3-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...) Show SMILES Nc1nccc(n1)-c1c[nH]c2CCNC(=O)c12 Show InChI InChI=1S/C11H11N5O/c12-11-14-4-1-7(16-11)6-5-15-8-2-3-13-10(17)9(6)8/h1,4-5,15H,2-3H2,(H,13,17)(H2,12,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	7.9	25
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B
					More data for this Ligand-Target Pair