BDBM27405 2-(2-aminopyrimidin-4-yl)-1-(2-hydroxyethyl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::pyrrolopyridinone scaffold, 27

SMILES: Nc1nccc(n1)-c1cc2c(CCNC2=O)n1CCO

InChI Key: InChIKey=FLXBGGNDSKKNSQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27405 (2-(2-aminopyrimidin-4-yl)-1-(2-hydroxyethyl)-1H,4H...) Show SMILES Nc1nccc(n1)-c1cc2c(CCNC2=O)n1CCO Show InChI InChI=1S/C13H15N5O2/c14-13-16-3-1-9(17-13)11-7-8-10(18(11)5-6-19)2-4-15-12(8)20/h1,3,7,19H,2,4-6H2,(H,15,20)(H2,14,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	7.9	25
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B
					More data for this Ligand-Target Pair