BDBM27417 2-(2-aminopyrimidin-4-yl)-1-benzyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::pyrrolopyridinone scaffold, 39

SMILES: Nc1nccc(n1)-c1cc2c(CCNC2=O)n1Cc1ccccc1

InChI Key: InChIKey=CTTKPAKQUBTEOG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27417 (2-(2-aminopyrimidin-4-yl)-1-benzyl-1H,4H,5H,6H,7H-...) Show SMILES Nc1nccc(n1)-c1cc2c(CCNC2=O)n1Cc1ccccc1 Show InChI InChI=1S/C18H17N5O/c19-18-21-8-6-14(22-18)16-10-13-15(7-9-20-17(13)24)23(16)11-12-4-2-1-3-5-12/h1-6,8,10H,7,9,11H2,(H,20,24)(H2,19,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B
					More data for this Ligand-Target Pair