BDBM27424 N-(4-{4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-2-yl}pyrimidin-2-yl)acetamide::pyrrolopyridinone scaffold, 46

SMILES: CC(=O)Nc1nccc(n1)-c1cc2c(CCNC2=O)[nH]1

InChI Key: InChIKey=IYIBUTZZEKKWBT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27424 (N-(4-{4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-2...) Show SMILES CC(=O)Nc1nccc(n1)-c1cc2c(CCNC2=O)[nH]1 Show InChI InChI=1S/C13H13N5O2/c1-7(19)16-13-15-5-3-10(18-13)11-6-8-9(17-11)2-4-14-12(8)20/h3,5-6,17H,2,4H2,1H3,(H,14,20)(H,15,16,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	323	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B
					More data for this Ligand-Target Pair