BDBM274704 N-(6-(4-(4-fluorophenyl)-1-(furan-3- ylmethyl)-1H-imidazol-5-yl)imidazo[1,2- b]pyridazin-2-yl)pivalamide::US9556179, Compound 279

SMILES: CC(C)(C)C(=O)Nc1cn2nc(ccc2n1)-c1c(ncn1Cc1ccoc1)-c1ccc(F)cc1

InChI Key: InChIKey=HWKVOPMKGABQLA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 274704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM274704 (N-(6-(4-(4-fluorophenyl)-1-(furan-3- ylmethyl)-1H-...) Show SMILES CC(C)(C)C(=O)Nc1cn2nc(ccc2n1)-c1c(ncn1Cc1ccoc1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H23FN6O2/c1-25(2,3)24(33)29-20-13-32-21(28-20)9-8-19(30-32)23-22(17-4-6-18(26)7-5-17)27-15-31(23)12-16-10-11-34-14-16/h4-11,13-15H,12H2,1-3H3,(H,29,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.169	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9556179 (2017) BindingDB Entry DOI: 10.7270/Q2G73GR5
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM274704 (N-(6-(4-(4-fluorophenyl)-1-(furan-3- ylmethyl)-1H-...) Show SMILES CC(C)(C)C(=O)Nc1cn2nc(ccc2n1)-c1c(ncn1Cc1ccoc1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H23FN6O2/c1-25(2,3)24(33)29-20-13-32-21(28-20)9-8-19(30-32)23-22(17-4-6-18(26)7-5-17)27-15-31(23)12-16-10-11-34-14-16/h4-11,13-15H,12H2,1-3H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.887	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9556179 (2017) BindingDB Entry DOI: 10.7270/Q2G73GR5
					More data for this Ligand-Target Pair