BDBM27495 6-chloro-2,3-dimethylimidazo[1,2-a]pyridin-8-ol::BYK20370

SMILES: Cc1nc2c(O)cc(Cl)cn2c1C

InChI Key: InChIKey=JJTUIIUDUVKJDA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
poly-ADP-ribose polymerase 2 (PARP2) (Mus musculus (Mouse))	BDBM27495 (6-chloro-2,3-dimethylimidazo[1,2-a]pyridin-8-ol | ...) Show SMILES Cc1nc2c(O)cc(Cl)cn2c1C Show InChI InChI=1S/C9H9ClN2O/c1-5-6(2)12-4-7(10)3-8(13)9(12)11-5/h3-4,13H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	7.8	22
University of Konstanz					Assay Description The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...				Mol Pharmacol 74: 1587-98 (2008) Article DOI: 10.1124/mol.108.048751 BindingDB Entry DOI: 10.7270/Q2M61HKG
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27495 (6-chloro-2,3-dimethylimidazo[1,2-a]pyridin-8-ol | ...) Show SMILES Cc1nc2c(O)cc(Cl)cn2c1C Show InChI InChI=1S/C9H9ClN2O/c1-5-6(2)12-4-7(10)3-8(13)9(12)11-5/h3-4,13H,1-2H3	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	7.8	22
University of Konstanz					Assay Description The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...				Mol Pharmacol 74: 1587-98 (2008) Article DOI: 10.1124/mol.108.048751 BindingDB Entry DOI: 10.7270/Q2M61HKG
					More data for this Ligand-Target Pair