BDBM274961 US9877957, Example 1
SMILES: COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CCN(CC2)c2ccc(cc2)C(F)(F)F)c2CN(CCc12)C(=O)NC(C)(C)C
InChI Key: InChIKey=GQMWGXUCLAWMPB-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human)) | BDBM274961 (US9877957, Example 1) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.75 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m... | US Patent US9877957 (2018) BindingDB Entry DOI: 10.7270/Q2Z60R2C | |||||||||||
More data for this Ligand-Target Pair |