BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM275947 US10071974, Example 58::US10071974, Example 59::US10071974, Example 60::US10577336, Example 60

SMILES: Cc1cccc2c(n[nH]c12)C(C)(C)NC(=O)C1CNCCOC1

InChI Key:

Data: 6 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 275947
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275947 (US10071974, Example 58 \| US10071974, Example 59 \| ...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.10	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...				US Patent US10071974 (2018) BindingDB Entry DOI: 10.7270/Q28G8NQ7
Boehringer Ingelheim International GmbH US Patent					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275947 (US10071974, Example 58 \| US10071974, Example 59 \| ...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...				US Patent US10071974 (2018) BindingDB Entry DOI: 10.7270/Q28G8NQ7
Boehringer Ingelheim International GmbH US Patent					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275947 (US10071974, Example 58 \| US10071974, Example 59 \| ...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10577336 (2020) BindingDB Entry DOI: 10.7270/Q24F1T4F
Boehringer Ingelheim International GmbH US Patent					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275947 (US10071974, Example 58 \| US10071974, Example 59 \| ...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10577336 (2020) BindingDB Entry DOI: 10.7270/Q24F1T4F
Boehringer Ingelheim International GmbH US Patent					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275947 (US10071974, Example 58 \| US10071974, Example 59 \| ...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10577336 (2020) BindingDB Entry DOI: 10.7270/Q24F1T4F
Boehringer Ingelheim International GmbH US Patent					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM275947 (US10071974, Example 58 \| US10071974, Example 59 \| ...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.30	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...				US Patent US10071974 (2018) BindingDB Entry DOI: 10.7270/Q28G8NQ7
Boehringer Ingelheim International GmbH US Patent					More data for this Ligand-Target Pair