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BDBM276064 2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]imidazol-44-yl]-4-(1H-triazol-4-yl)pyridine::US10071984, Example 26::US10174003, Example 26

SMILES: Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F

InChI Key:

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276064   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (Human))
BDBM276064
PNG
(2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]...)
Show SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent




US Patent US10071984 (2018)


BindingDB Entry DOI: 10.7270/Q24Q7X0X
More data for this
Ligand-Target Pair
Histone lysine demethylase PHF8


(Homo sapiens (Human))
BDBM276064
PNG
(2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]...)
Show SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent




US Patent US10174003 (2019)


BindingDB Entry DOI: 10.7270/Q2417053
More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (Human))
BDBM276064
PNG
(2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]...)
Show SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent




US Patent US10174003 (2019)


BindingDB Entry DOI: 10.7270/Q2417053
More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (Human))
BDBM276064
PNG
(2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]...)
Show SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent




US Patent US10071984 (2018)


BindingDB Entry DOI: 10.7270/Q24Q7X0X
More data for this
Ligand-Target Pair