BDBM276114 2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-4-yl]methoxy]-4-methyl-::US10071988, Example 21::US10233173, Example 21

SMILES: Cc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1

InChI Key: InChIKey=CKXJAQCEYVFZAM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM276114 (2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-...) Show SMILES Cc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1 Show InChI InChI=1S/C15H12ClF2N5O2/c1-9-4-5-19-15(20-9)24-8-10-7-23(22-21-10)11-2-3-12(16)13(6-11)25-14(17)18/h2-7,14H,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Lund University					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				Bioorg Med Chem 14: 1215-20 (2006) BindingDB Entry DOI: 10.7270/Q23R0W6K
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM276114 (2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-...) Show SMILES Cc1ccnc(OCc2cn(nn2)-c2ccc(Cl)c(OC(F)F)c2)n1 Show InChI InChI=1S/C15H12ClF2N5O2/c1-9-4-5-19-15(20-9)24-8-10-7-23(22-21-10)11-2-3-12(16)13(6-11)25-14(17)18/h2-7,14H,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	25
JANSSEN PHARMACEUTICA NV US Patent					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				US Patent US10071988 (2018) BindingDB Entry DOI: 10.7270/Q20Z7591
					More data for this Ligand-Target Pair