BDBM276121 5-Chloro-2-[[1-[4-chloro-3-(difluoromethoxy)phenyl]triazol-4-::US10071988, Example 28::US10233173, Example 28

SMILES: FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncc(Cl)cn2)nn1

InChI Key: InChIKey=ZYIVRWRHTNYLOL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM276121 (5-Chloro-2-[[1-[4-chloro-3-(difluoromethoxy)phenyl...) Show SMILES FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncc(Cl)cn2)nn1 Show InChI InChI=1S/C14H9Cl2F2N5O2/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-11(16)12(3-10)25-13(17)18/h1-6,13H,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Lund University					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				Bioorg Med Chem 14: 1215-20 (2006) BindingDB Entry DOI: 10.7270/Q23R0W6K
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM276121 (5-Chloro-2-[[1-[4-chloro-3-(difluoromethoxy)phenyl...) Show SMILES FC(F)Oc1cc(ccc1Cl)-n1cc(COc2ncc(Cl)cn2)nn1 Show InChI InChI=1S/C14H9Cl2F2N5O2/c15-8-4-19-14(20-5-8)24-7-9-6-23(22-21-9)10-1-2-11(16)12(3-10)25-13(17)18/h1-6,13H,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	25
JANSSEN PHARMACEUTICA NV US Patent					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				US Patent US10071988 (2018) BindingDB Entry DOI: 10.7270/Q20Z7591
					More data for this Ligand-Target Pair