BDBM276536 5-Chloro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-::US10071988, Example 476::US10233173, Example 476

SMILES: Cc1cc(ccc1F)-n1cc(COc2ncc(Cl)cn2)nn1

InChI Key: InChIKey=UOOXQHCSQXAAAC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM276536 (5-Chloro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4...) Show SMILES Cc1cc(ccc1F)-n1cc(COc2ncc(Cl)cn2)nn1 Show InChI InChI=1S/C14H11ClFN5O/c1-9-4-12(2-3-13(9)16)21-7-11(19-20-21)8-22-14-17-5-10(15)6-18-14/h2-7H,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Lund University					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				Bioorg Med Chem 14: 1215-20 (2006) BindingDB Entry DOI: 10.7270/Q23R0W6K
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM276536 (5-Chloro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4...) Show SMILES Cc1cc(ccc1F)-n1cc(COc2ncc(Cl)cn2)nn1 Show InChI InChI=1S/C14H11ClFN5O/c1-9-4-12(2-3-13(9)16)21-7-11(19-20-21)8-22-14-17-5-10(15)6-18-14/h2-7H,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	25
JANSSEN PHARMACEUTICA NV US Patent					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				US Patent US10071988 (2018) BindingDB Entry DOI: 10.7270/Q20Z7591
					More data for this Ligand-Target Pair