BDBM276537 2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl-::US10071988, Example 477::US10233173, Example 477

SMILES: Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2)nc1

InChI Key: InChIKey=XVXPBMJKCJQWIF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM276537 (2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]metho...) Show SMILES Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2)nc1 Show InChI InChI=1S/C15H14FN5O/c1-10-6-17-15(18-7-10)22-9-12-8-21(20-19-12)13-3-4-14(16)11(2)5-13/h3-8H,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Lund University					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				Bioorg Med Chem 14: 1215-20 (2006) BindingDB Entry DOI: 10.7270/Q23R0W6K
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM276537 (2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]metho...) Show SMILES Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(C)c2)nc1 Show InChI InChI=1S/C15H14FN5O/c1-10-6-17-15(18-7-10)22-9-12-8-21(20-19-12)13-3-4-14(16)11(2)5-13/h3-8H,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	25
JANSSEN PHARMACEUTICA NV US Patent					Assay Description NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...				US Patent US10071988 (2018) BindingDB Entry DOI: 10.7270/Q20Z7591
					More data for this Ligand-Target Pair