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BDBM276752 2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(3- methyl-1,1-dioxidotetra- hydrothiophen-3-yl) pyrimidine-5-carboxamide::US10071992, Example 3.1

SMILES: CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1(C)CCS(=O)(=O)C1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 276752   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))
BDBM276752
PNG
(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(...)
Show SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1(C)CCS(=O)(=O)C1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13.5n/an/an/an/a7.425



Pfizer Inc.

US Patent




US Patent US10071992 (2018)


BindingDB Entry DOI: 10.7270/Q2RJ4MHN
More data for this
Ligand-Target Pair