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SMILES: CCOc1cccnc1Oc1cncc(c1)-c1ncc(nn1)C(=O)NC(C)(C)CO

InChI Key: InChIKey=ZVQDMWKMNDSSSS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM276762 (US10071992, Example 7 | US11034678, Example 7) Show SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(nn1)C(=O)NC(C)(C)CO Show InChI InChI=1S/C20H22N6O4/c1-4-29-16-6-5-7-22-19(16)30-14-8-13(9-21-10-14)17-23-11-15(25-26-17)18(28)24-20(2,3)12-27/h5-11,27H,4,12H2,1-3H3,(H,24,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM276762 (US10071992, Example 7 | US11034678, Example 7) Show SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(nn1)C(=O)NC(C)(C)CO Show InChI InChI=1S/C20H22N6O4/c1-4-29-16-6-5-7-22-19(16)30-14-8-13(9-21-10-14)17-23-11-15(25-26-17)18(28)24-20(2,3)12-27/h5-11,27H,4,12H2,1-3H3,(H,24,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	83	n/a	n/a	n/a	n/a	7.4	25
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...				US Patent US10071992 (2018) BindingDB Entry DOI: 10.7270/Q2RJ4MHN
					More data for this Ligand-Target Pair