BDBM27746 (2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-propylphenyl)carbamoyl]amino}-4-(3-fluorophenyl)phenyl)formamido]butanoic acid::anthranilimide based compound, 22
SMILES: CCCc1cc(C)c(NC(=O)Nc2cc(ccc2C(=O)N[C@@H]([C@@H](C)OC(C)(C)C)C(O)=O)-c2cccc(F)c2)c(C)c1
InChI Key: InChIKey=HUGDXVNYJFTTHO-PBBNMVCDSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human)) | BDBM27746 ((2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-pr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.6 | 25 |
GSK | Assay Description An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t... | Bioorg Med Chem Lett 19: 1177-82 (2009) Article DOI: 10.1016/j.bmcl.2008.12.085 BindingDB Entry DOI: 10.7270/Q22805ZM | |||||||||||
More data for this Ligand-Target Pair |