BDBM279455 (R)-1-(5-(1H-pyrrolo[2, 3-b]pyridin-4-yl)-1H-benzo[d]imidazol-2-yl)-3-methylbutan-1-amine::US10035777, Example 6

SMILES: CC(C)C[C@@H](NC(=O)OCc1ccccc1)c1nc2ccc(cc2[nH]1)B(O)O

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM279455 ((R)-1-(5-(1H-pyrrolo[2, 3-b]pyridin-4-yl)-1H-benzo...) Show SMILES CC(C)C[C@@H](NC(=O)OCc1ccccc1)c1nc2ccc(cc2[nH]1)B(O)O |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10035777 (2018) BindingDB Entry DOI: 10.7270/Q28C9Z8G
					More data for this Ligand-Target Pair