BDBM27982 2-[benzyl(methyl)amino]-N-(2-phenoxyethyl)-4-(3,4,5-trimethoxyphenyl)pyrimidine-5-carboxamide::trisubstituted pyrimidine analogue, 6c

SMILES: COc1cc(cc(OC)c1OC)-c1nc(ncc1C(=O)NCCOc1ccccc1)N(C)Cc1ccccc1

InChI Key: InChIKey=PPXZFMRUTAQVCT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27982   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM27982 (2-[benzyl(methyl)amino]-N-(2-phenoxyethyl)-4-(3,4,...) Show SMILES COc1cc(cc(OC)c1OC)-c1nc(ncc1C(=O)NCCOc1ccccc1)N(C)Cc1ccccc1 Show InChI InChI=1S/C30H32N4O5/c1-34(20-21-11-7-5-8-12-21)30-32-19-24(29(35)31-15-16-39-23-13-9-6-10-14-23)27(33-30)22-17-25(36-2)28(38-4)26(18-22)37-3/h5-14,17-19H,15-16,20H2,1-4H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	7.5	37
Bristol-Myers Squibb Company					Assay Description Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...				J Med Chem 52: 1204-8 (2009) Article DOI: 10.1021/jm801178c BindingDB Entry DOI: 10.7270/Q2416VCR
					More data for this Ligand-Target Pair