BDBM28006 2-[benzyl(methyl)amino]-4-(3-methoxyphenyl)-N-(2-phenoxyethyl)pyrimidine-5-carboxamide::trisubstituted pyrimidine analogue, 11g

SMILES: COc1cccc(c1)-c1nc(ncc1C(=O)NCCOc1ccccc1)N(C)Cc1ccccc1

InChI Key: InChIKey=UXUOKLNDJZQSCD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM28006 (2-[benzyl(methyl)amino]-4-(3-methoxyphenyl)-N-(2-p...) Show SMILES COc1cccc(c1)-c1nc(ncc1C(=O)NCCOc1ccccc1)N(C)Cc1ccccc1 Show InChI InChI=1S/C28H28N4O3/c1-32(20-21-10-5-3-6-11-21)28-30-19-25(26(31-28)22-12-9-15-24(18-22)34-2)27(33)29-16-17-35-23-13-7-4-8-14-23/h3-15,18-19H,16-17,20H2,1-2H3,(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.5	37
Bristol-Myers Squibb Company					Assay Description Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...				J Med Chem 52: 1204-8 (2009) Article DOI: 10.1021/jm801178c BindingDB Entry DOI: 10.7270/Q2416VCR
					More data for this Ligand-Target Pair