BDBM28009 2-[benzyl(methyl)amino]-4-(3,4-dimethoxyphenyl)-N-(2-phenoxyethyl)pyrimidine-5-carboxamide::trisubstituted pyrimidine analogue, 11j

SMILES: COc1ccc(cc1OC)-c1nc(ncc1C(=O)NCCOc1ccccc1)N(C)Cc1ccccc1

InChI Key: InChIKey=HNBYJJHYXFYQAT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM28009 (2-[benzyl(methyl)amino]-4-(3,4-dimethoxyphenyl)-N-...) Show SMILES COc1ccc(cc1OC)-c1nc(ncc1C(=O)NCCOc1ccccc1)N(C)Cc1ccccc1 Show InChI InChI=1S/C29H30N4O4/c1-33(20-21-10-6-4-7-11-21)29-31-19-24(28(34)30-16-17-37-23-12-8-5-9-13-23)27(32-29)22-14-15-25(35-2)26(18-22)36-3/h4-15,18-19H,16-17,20H2,1-3H3,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...				J Med Chem 52: 1204-8 (2009) Article DOI: 10.1021/jm801178c BindingDB Entry DOI: 10.7270/Q2416VCR
					More data for this Ligand-Target Pair