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BDBM28015 6-[benzyl(ethyl)amino]-N-(2-phenoxyethyl)-2-(3,4,5-trimethoxyphenyl)pyridine-3-carboxamide::trisubstituted pyridine analogue, 18a

SMILES: CCN(Cc1ccccc1)c1ccc(C(=O)NCCOc2ccccc2)c(n1)-c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=GTLDSUZUODVBJX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28015   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))		BDBM28015
PNG
(6-[benzyl(ethyl)amino]-N-(2-phenoxyethyl)-2-(3,4,5...)
Show SMILES CCN(Cc1ccccc1)c1ccc(C(=O)NCCOc2ccccc2)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C32H35N3O5/c1-5-35(22-23-12-8-6-9-13-23)29-17-16-26(32(36)33-18-19-40-25-14-10-7-11-15-25)30(34-29)24-20-27(37-2)31(39-4)28(21-24)38-3/h6-17,20-21H,5,18-19,22H2,1-4H3,(H,33,36)
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Article
PubMed
n/an/a 154n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...

J Med Chem 52: 1204-8 (2009)


Article DOI: 10.1021/jm801178c
BindingDB Entry DOI: 10.7270/Q2416VCR
More data for this
Ligand-Target Pair