BDBM280297 US10029993, Example 86

SMILES: Cc1ccccc1-c1cnnc(n1)N1CCN(CC(=O)Nc2cccnc2)CC1

InChI Key: InChIKey=SPSOLFRKRWUGKM-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM280297 (US10029993, Example 86) Show SMILES Cc1ccccc1-c1cnnc(n1)N1CCN(CC(=O)Nc2cccnc2)CC1 Show InChI InChI=1S/C21H23N7O/c1-16-5-2-3-7-18(16)19-14-23-26-21(25-19)28-11-9-27(10-12-28)15-20(29)24-17-6-4-8-22-13-17/h2-8,13-14H,9-12,15H2,1H3,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.4	25
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The pcDNA3.1-human CYP11B2 plasmid was transfected into a Chinese hamster lung fibroblast V79 cell line to produce a cell line stably expressing huma...				US Patent US10029993 (2018) BindingDB Entry DOI: 10.7270/Q2V40X6M
					More data for this Ligand-Target Pair