BDBM280316 US10029993, Example 183

SMILES: Cc1ccccc1-c1cnnc(n1)N1CCC(CCCO)CC1

InChI Key: InChIKey=PNDWSCMRHIEJSP-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM280316 (US10029993, Example 183) Show SMILES Cc1ccccc1-c1cnnc(n1)N1CCC(CCCO)CC1 Show InChI InChI=1S/C18H24N4O/c1-14-5-2-3-7-16(14)17-13-19-21-18(20-17)22-10-8-15(9-11-22)6-4-12-23/h2-3,5,7,13,15,23H,4,6,8-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.4	25
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The pcDNA3.1-human CYP11B2 plasmid was transfected into a Chinese hamster lung fibroblast V79 cell line to produce a cell line stably expressing huma...				US Patent US10029993 (2018) BindingDB Entry DOI: 10.7270/Q2V40X6M
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