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SMILES: CCOC(=O)N1CCCC(CC1)N1CCC(CC1)c1cccnc1OCc1cc(C)no1

InChI Key: InChIKey=NRTNZXTVAZBGRR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280424   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))		BDBM280424
PNG
(US10030012, Example 54 | ethyl 4-(4-{2-[(3- methyl...)
Show SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)c1cccnc1OCc1cc(C)no1
Show InChI InChI=1S/C24H34N4O4/c1-3-30-24(29)28-12-5-6-20(10-15-28)27-13-8-19(9-14-27)22-7-4-11-25-23(22)31-17-21-16-18(2)26-32-21/h4,7,11,16,19-20H,3,5-6,8-10,12-15,17H2,1-2H3
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US Patent
n/an/an/an/a 20n/an/an/an/a



Heptares Therapeutics Limited

US Patent


Assay Description
The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...

US Patent US10030012 (2018)


BindingDB Entry DOI: 10.7270/Q2KK9DTW
More data for this
Ligand-Target Pair