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SMILES: FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(cc(c2)C(F)(F)F)N2CCOCC2)CC1)C(F)(F)F

InChI Key: InChIKey=DOWABTHPANITFZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 280490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Mus musculus (mouse))	BDBM280490 (US10030020, Example 35 | US10781211, Example 204) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(cc(c2)C(F)(F)F)N2CCOCC2)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-12-16(13-18(14-17)34-8-10-38-11-9-34)15-36-5-1-2-21(36)3-6-35(7-4-21)20(37)39-19(23(28,29)30)24(31,32)33/h12-14,19H,1-11,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Mus musculus (mouse))	BDBM280490 (US10030020, Example 35 | US10781211, Example 204) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(cc(c2)C(F)(F)F)N2CCOCC2)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-12-16(13-18(14-17)34-8-10-38-11-9-34)15-36-5-1-2-21(36)3-6-35(7-4-21)20(37)39-19(23(28,29)30)24(31,32)33/h12-14,19H,1-11,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD2 (Mus musculus (Mouse))	BDBM280490 (US10030020, Example 35 | US10781211, Example 204) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(cc(c2)C(F)(F)F)N2CCOCC2)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-12-16(13-18(14-17)34-8-10-38-11-9-34)15-36-5-1-2-21(36)3-6-35(7-4-21)20(37)39-19(23(28,29)30)24(31,32)33/h12-14,19H,1-11,15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM280490 (US10030020, Example 35 | US10781211, Example 204) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(cc(c2)C(F)(F)F)N2CCOCC2)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-12-16(13-18(14-17)34-8-10-38-11-9-34)15-36-5-1-2-21(36)3-6-35(7-4-21)20(37)39-19(23(28,29)30)24(31,32)33/h12-14,19H,1-11,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description Human: Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with ...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Mus musculus (mouse))	BDBM280490 (US10030020, Example 35 | US10781211, Example 204) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(cc(c2)C(F)(F)F)N2CCOCC2)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-12-16(13-18(14-17)34-8-10-38-11-9-34)15-36-5-1-2-21(36)3-6-35(7-4-21)20(37)39-19(23(28,29)30)24(31,32)33/h12-14,19H,1-11,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280490 (US10030020, Example 35 | US10781211, Example 204) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(cc(c2)C(F)(F)F)N2CCOCC2)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-12-16(13-18(14-17)34-8-10-38-11-9-34)15-36-5-1-2-21(36)3-6-35(7-4-21)20(37)39-19(23(28,29)30)24(31,32)33/h12-14,19H,1-11,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoglyceride lipase (Mus musculus (mouse))	BDBM280490 (US10030020, Example 35 | US10781211, Example 204) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(cc(c2)C(F)(F)F)N2CCOCC2)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-12-16(13-18(14-17)34-8-10-38-11-9-34)15-36-5-1-2-21(36)3-6-35(7-4-21)20(37)39-19(23(28,29)30)24(31,32)33/h12-14,19H,1-11,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair