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SMILES: FC1CCN(CC1)c1cccc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1Cl

InChI Key: InChIKey=ZQXCBJDAUQKZIL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 280565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Mus musculus (mouse))	BDBM280565 (US10030020, Example 110 | US10781211, Example 110) Show SMILES FC1CCN(CC1)c1cccc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1Cl Show InChI InChI=1S/C24H29ClF7N3O2/c25-19-16(3-1-4-18(19)33-11-5-17(26)6-12-33)15-35-10-2-7-22(35)8-13-34(14-9-22)21(36)37-20(23(27,28)29)24(30,31)32/h1,3-4,17,20H,2,5-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Mus musculus (mouse))	BDBM280565 (US10030020, Example 110 | US10781211, Example 110) Show SMILES FC1CCN(CC1)c1cccc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1Cl Show InChI InChI=1S/C24H29ClF7N3O2/c25-19-16(3-1-4-18(19)33-11-5-17(26)6-12-33)15-35-10-2-7-22(35)8-13-34(14-9-22)21(36)37-20(23(27,28)29)24(30,31)32/h1,3-4,17,20H,2,5-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280565 (US10030020, Example 110 | US10781211, Example 110) Show SMILES FC1CCN(CC1)c1cccc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1Cl Show InChI InChI=1S/C24H29ClF7N3O2/c25-19-16(3-1-4-18(19)33-11-5-17(26)6-12-33)15-35-10-2-7-22(35)8-13-34(14-9-22)21(36)37-20(23(27,28)29)24(30,31)32/h1,3-4,17,20H,2,5-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoglyceride lipase (Mus musculus (mouse))	BDBM280565 (US10030020, Example 110 | US10781211, Example 110) Show SMILES FC1CCN(CC1)c1cccc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1Cl Show InChI InChI=1S/C24H29ClF7N3O2/c25-19-16(3-1-4-18(19)33-11-5-17(26)6-12-33)15-35-10-2-7-22(35)8-13-34(14-9-22)21(36)37-20(23(27,28)29)24(30,31)32/h1,3-4,17,20H,2,5-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Mus musculus (mouse))	BDBM280565 (US10030020, Example 110 | US10781211, Example 110) Show SMILES FC1CCN(CC1)c1cccc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1Cl Show InChI InChI=1S/C24H29ClF7N3O2/c25-19-16(3-1-4-18(19)33-11-5-17(26)6-12-33)15-35-10-2-7-22(35)8-13-34(14-9-22)21(36)37-20(23(27,28)29)24(30,31)32/h1,3-4,17,20H,2,5-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD2 (Mus musculus (Mouse))	BDBM280565 (US10030020, Example 110 | US10781211, Example 110) Show SMILES FC1CCN(CC1)c1cccc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1Cl Show InChI InChI=1S/C24H29ClF7N3O2/c25-19-16(3-1-4-18(19)33-11-5-17(26)6-12-33)15-35-10-2-7-22(35)8-13-34(14-9-22)21(36)37-20(23(27,28)29)24(30,31)32/h1,3-4,17,20H,2,5-15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair