BDBM280588 US10030020, Example 133::US10781211, Example 133

SMILES: FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F

InChI Key: InChIKey=NTRGSBXESFOVEI-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 280588   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280588 (US10030020, Example 133 | US10781211, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Mus musculus (mouse))	BDBM280588 (US10030020, Example 133 | US10781211, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD2 (Mus musculus (Mouse))	BDBM280588 (US10030020, Example 133 | US10781211, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM280588 (US10030020, Example 133 | US10781211, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description Human: Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with ...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280588 (US10030020, Example 133 | US10781211, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Mus musculus (mouse))	BDBM280588 (US10030020, Example 133 | US10781211, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280588 (US10030020, Example 133 | US10781211, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM280588 (US10030020, Example 133 | US10781211, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair