BDBM281261 US10022354, Example 201
SMILES: CC(C)Oc1ccccc1C(=O)NC1CCN(C1)C(=O)c1cc(n[nH]1)C(C)C
InChI Key: InChIKey=CTDHTIBLOGVFNE-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 5A (Homo sapiens (Human)) | BDBM281261 (US10022354, Example 201) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0920 | n/a | n/a | n/a | n/a | 7.0 | 25 |
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS INC. US Patent | Assay Description Full length KDM5A enzyme was expressed and purified inhouse. Biotin-H3K4me3 peptide was purchased from New England Biolabs. HTRF reagents (containing... | US Patent US10022354 (2018) BindingDB Entry DOI: 10.7270/Q2PC34F7 | |||||||||||
More data for this Ligand-Target Pair |