BDBM281282 US10022354, Example 222
SMILES: CC(C)c1cc([nH]n1)C(=O)N1CC[C@H](C1)NC(=O)[C@H]1C[C@H]1F
InChI Key:
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 5A (Homo sapiens (Human)) | BDBM281282 (US10022354, Example 222) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0250 | n/a | n/a | n/a | n/a | 7.0 | 25 |
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS INC. US Patent | Assay Description Full length KDM5A enzyme was expressed and purified inhouse. Biotin-H3K4me3 peptide was purchased from New England Biolabs. HTRF reagents (containing... | US Patent US10022354 (2018) BindingDB Entry DOI: 10.7270/Q2PC34F7 | |||||||||||
More data for this Ligand-Target Pair |