BDBM28239 2-(7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2-yl}-8-hydroxy-1,6-naphthyridin-5-yl)-1,2-thiazinane-1,1-dione::BMCL191807 Compound 2::C5-sultam substituted naphthyridine, 33

SMILES: Oc1c(nc(N2CCCCS2(=O)=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1

InChI Key: InChIKey=PKDXCDDPOQGIND-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Integrase (Human immunodeficiency virus type 1)	BDBM28239 (2-(7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2...) Show SMILES Oc1c(nc(N2CCCCS2(=O)=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H18FN5O4S/c22-14-7-5-13(6-8-14)12-16-25-26-21(31-16)18-19(28)17-15(4-3-9-23-17)20(24-18)27-10-1-2-11-32(27,29)30/h3-9,28H,1-2,10-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1802-6 (2009) Article DOI: 10.1016/j.bmcl.2009.01.090 BindingDB Entry DOI: 10.7270/Q2Z899QM
					More data for this Ligand-Target Pair
HIV-1 Integrase (Human immunodeficiency virus type 1)	BDBM28239 (2-(7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2...) Show SMILES Oc1c(nc(N2CCCCS2(=O)=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H18FN5O4S/c22-14-7-5-13(6-8-14)12-16-25-26-21(31-16)18-19(28)17-15(4-3-9-23-17)20(24-18)27-10-1-2-11-32(27,29)30/h3-9,28H,1-2,10-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair