null
SMILES: CCN(C1CN(N=C1c1ccc(Cl)c(Cl)c1)C(\Nc1cccc(OC(F)F)c1)=N/C#N)C(=O)CN
InChI Key: InChIKey=NYIWCWBYWZAIAY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM283132 (Rac-N-[1-{N′-cyano-N-[3-(difluoromethoxy)phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 101 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip... | US Patent US10023539 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM283132 (Rac-N-[1-{N′-cyano-N-[3-(difluoromethoxy)phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 9.0 | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea... | US Patent US10023539 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RKD | |||||||||||
More data for this Ligand-Target Pair |