null
SMILES: C[C@@H](Oc1cccc(N2CCNCC2)c1C)c1ccccc1
InChI Key: InChIKey=QUJJFIRUSWFDCL-MRXNPFEDSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28593 (1-{2-methyl-3-[(1R)-1-phenylethoxy]phenyl}piperazi...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 70.7 | -9.65 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair |