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BDBM28602 4-{3-[(1R)-1-(3-fluorophenyl)ethoxy]-2-methylphenyl}piperidine::tolylpiperidine, 9j

SMILES: C[C@@H](Oc1cccc(C2CCNCC2)c1C)c1cccc(F)c1

InChI Key: InChIKey=VLFJECXUHXIQBJ-OAHLLOKOSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28602   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM28602
PNG
(4-{3-[(1R)-1-(3-fluorophenyl)ethoxy]-2-methylpheny...)
Show SMILES C[C@@H](Oc1cccc(C2CCNCC2)c1C)c1cccc(F)c1 |r|
Show InChI InChI=1S/C20H24FNO/c1-14-19(16-9-11-22-12-10-16)7-4-8-20(14)23-15(2)17-5-3-6-18(21)13-17/h3-8,13,15-16,22H,9-12H2,1-2H3/t15-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
39.8 -9.99n/an/an/an/an/a7.522



Pfizer



Assay Description
Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...


Bioorg Med Chem Lett 19: 2409-12 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q24T6GP5
More data for this
Ligand-Target Pair