null

SMILES: CN1CCN(Cc2c[nH]c3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1

InChI Key: InChIKey=VSLDKPAIVWRXRV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM286077 (1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-...) Show SMILES CN1CCN(Cc2c[nH]c3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1 Show InChI InChI=1S/C25H28N6O/c1-29-9-11-30(12-10-29)17-20-14-26-24-13-22(7-8-23(20)24)28-25(32)21-15-27-31(18-21)16-19-5-3-2-4-6-19/h2-8,13-15,18,26H,9-12,16-17H2,1H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGNS US Patent					Assay Description The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...				US Patent US10081632 (2018) BindingDB Entry DOI: 10.7270/Q2VT1V45
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286077 (1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-...) Show SMILES CN1CCN(Cc2c[nH]c3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1 Show InChI InChI=1S/C25H28N6O/c1-29-9-11-30(12-10-29)17-20-14-26-24-13-22(7-8-23(20)24)28-25(32)21-15-27-31(18-21)16-19-5-3-2-4-6-19/h2-8,13-15,18,26H,9-12,16-17H2,1H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGNS US Patent					Assay Description Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...				US Patent US10758530 (2020)
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286077 (1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-...) Show SMILES CN1CCN(Cc2c[nH]c3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1 Show InChI InChI=1S/C25H28N6O/c1-29-9-11-30(12-10-29)17-20-14-26-24-13-22(7-8-23(20)24)28-25(32)21-15-27-31(18-21)16-19-5-3-2-4-6-19/h2-8,13-15,18,26H,9-12,16-17H2,1H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair