BDBM286083 1-benzyl-N-(3-(piperazin-1-ylmethyl)benzofuran-6-yl)-1H-pyrazole-4-carboxamide::US10081632, Compound 10::US10758530, Compound 10

SMILES: CC(C)(C)OC(=O)N1CCN(Cc2coc3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1

InChI Key: InChIKey=GYFANGIFZZUOEK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha 2 (RSK2) (Homo sapiens (Human))	BDBM286083 (1-benzyl-N-(3-(piperazin-1-ylmethyl)benzofuran-6-y...) Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2coc3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1 Show InChI InChI=1S/C29H33N5O4/c1-29(2,3)38-28(36)33-13-11-32(12-14-33)18-23-20-37-26-15-24(9-10-25(23)26)31-27(35)22-16-30-34(19-22)17-21-7-5-4-6-8-21/h4-10,15-16,19-20H,11-14,17-18H2,1-3H3,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGNS US Patent					Assay Description Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...				US Patent US10758530 (2020)
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM286083 (1-benzyl-N-(3-(piperazin-1-ylmethyl)benzofuran-6-y...) Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2coc3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1 Show InChI InChI=1S/C29H33N5O4/c1-29(2,3)38-28(36)33-13-11-32(12-14-33)18-23-20-37-26-15-24(9-10-25(23)26)31-27(35)22-16-30-34(19-22)17-21-7-5-4-6-8-21/h4-10,15-16,19-20H,11-14,17-18H2,1-3H3,(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGNS US Patent					Assay Description The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...				US Patent US10081632 (2018) BindingDB Entry DOI: 10.7270/Q2VT1V45
					More data for this Ligand-Target Pair