BindingDB logo
myBDB logout

null

SMILES: Cc1c(OCc2cccc(c2)C(F)(F)F)nccc1C1CCNCC1

InChI Key: InChIKey=YECNKJKNQYEFGX-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28609   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM28609
PNG
(3-methyl-4-(piperidin-4-yl)-2-{[3-(trifluoromethyl...)
Show SMILES Cc1c(OCc2cccc(c2)C(F)(F)F)nccc1C1CCNCC1
Show InChI InChI=1S/C19H21F3N2O/c1-13-17(15-5-8-23-9-6-15)7-10-24-18(13)25-12-14-3-2-4-16(11-14)19(20,21)22/h2-4,7,10-11,15,23H,5-6,8-9,12H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 19.1 -10.5n/an/an/an/an/an/a25



Pfizer



Assay Description
Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...

Bioorg Med Chem Lett 19: 2409-12 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q24T6GP5
More data for this
Ligand-Target Pair