BindingDB logo
myBDB logout

null

SMILES: Cc1c(OCc2ccccc2F)nccc1C1CCNCC1

InChI Key: InChIKey=HXOPTJFXVGDXBQ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28612   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM28612
PNG
(2-[(2-fluorophenyl)methoxy]-3-methyl-4-(piperidin-...)
Show SMILES Cc1c(OCc2ccccc2F)nccc1C1CCNCC1
Show InChI InChI=1S/C18H21FN2O/c1-13-16(14-6-9-20-10-7-14)8-11-21-18(13)22-12-15-4-2-3-5-17(15)19/h2-5,8,11,14,20H,6-7,9-10,12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
>440>-8.67n/an/an/an/an/an/a25



Pfizer



Assay Description
Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...

Bioorg Med Chem Lett 19: 2409-12 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q24T6GP5
More data for this
Ligand-Target Pair