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SMILES: C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(ncc3F)N(C)C)n[nH]c2C1(C)C

InChI Key: InChIKey=QECHNSUNXZVJGC-ZDUSSCGKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286231   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-tyrosine kinase 2-beta


(Homo sapiens (Human))		BDBM286231
PNG
(US9518060, Example A2)
Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(ncc3F)N(C)C)n[nH]c2C1(C)C |r|
Show InChI InChI=1S/C22H34FN9O/c1-13-10-30(8)21(2,3)12-31(13)20(33)32-11-14-16(22(32,4)5)27-28-17(14)25-18-15(23)9-24-19(26-18)29(6)7/h9,13H,10-12H2,1-8H3,(H2,24,25,26,27,28)/t13-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
 8.75n/an/an/an/an/an/a7.4n/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...

US Patent US9518060 (2016)


BindingDB Entry DOI: 10.7270/Q2ZK5JPN
More data for this
Ligand-Target Pair