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BDBM28625 2-methyl-3-(piperidin-4-yl)phenyl benzenesulfonate::tolylpiperidine, 18a

SMILES: Cc1c(OS(=O)(=O)c2ccccc2)cccc1C1CCNCC1

InChI Key: InChIKey=FHSWWFYSXOSTCT-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28625   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM28625
PNG
(2-methyl-3-(piperidin-4-yl)phenyl benzenesulfonate...)
Show SMILES Cc1c(OS(=O)(=O)c2ccccc2)cccc1C1CCNCC1
Show InChI InChI=1S/C18H21NO3S/c1-14-17(15-10-12-19-13-11-15)8-5-9-18(14)22-23(20,21)16-6-3-2-4-7-16/h2-9,15,19H,10-13H2,1H3
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PC cid
PC sid
UniChem
Article
PubMed
19.6 -10.5n/an/an/an/an/an/a25



Pfizer



Assay Description
Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...


Bioorg Med Chem Lett 19: 2409-12 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q24T6GP5
More data for this
Ligand-Target Pair