BDBM286264 US9518060, Example B6

SMILES: C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3ccnc(n3)C#N)n[nH]c2C1(C)C

InChI Key: InChIKey=AILQOERCUFVJMB-OLZOCXBDSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PTK2B protein tyrosine kinase 2 beta (PTK2B) (Homo sapiens (Human))	BDBM286264 (US9518060, Example B6) Show SMILES C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3ccnc(n3)C#N)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C20H27N9O/c1-12-10-28(13(2)9-27(12)5)19(30)29-11-14-17(20(29,3)4)25-26-18(14)24-15-6-7-22-16(8-21)23-15/h6-7,12-13H,9-11H2,1-5H3,(H2,22,23,24,25,26)/t12-,13+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.43	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair