null
SMILES: C[C@H]1CN2CCC[C@H]2CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C beta type (Homo sapiens (Human)) | BDBM286318 (US11220518, Ex. No. J5 | US9518060, Example J5) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a... | Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine kinase 2-beta (Homo sapiens (Human)) | BDBM286318 (US11220518, Ex. No. J5 | US9518060, Example J5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.43 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
PFIZER INC. US Patent | Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe... | US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN | |||||||||||
More data for this Ligand-Target Pair |