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SMILES: C[C@H]1CN2CCC[C@H]2CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C beta type (Homo sapiens (Human))	BDBM286318 (US11220518, Ex. No. J5 | US9518060, Example J5) Show SMILES C[C@H]1CN2CCC[C@H]2CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286318 (US11220518, Ex. No. J5 | US9518060, Example J5) Show SMILES C[C@H]1CN2CCC[C@H]2CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.43	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair