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SMILES: COCCCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C

InChI Key: InChIKey=HPQAVQJTTFEWSN-CABCVRRESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C beta type (Homo sapiens (Human))	BDBM286348 (US11220518, Ex. No. K6 | US9518060, Example K6) Show SMILES COCCCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C24H34F4N8O3/c1-14-11-35(15(2)10-34(14)7-6-8-38-5)22(37)36-12-16-18(23(36,3)4)32-33-19(16)30-20-17(25)9-29-21(31-20)39-13-24(26,27)28/h9,14-15H,6-8,10-13H2,1-5H3,(H2,29,30,31,32,33)/t14-,15+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.376	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286348 (US11220518, Ex. No. K6 | US9518060, Example K6) Show SMILES COCCCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C24H34F4N8O3/c1-14-11-35(15(2)10-34(14)7-6-8-38-5)22(37)36-12-16-18(23(36,3)4)32-33-19(16)30-20-17(25)9-29-21(31-20)39-13-24(26,27)28/h9,14-15H,6-8,10-13H2,1-5H3,(H2,29,30,31,32,33)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.376	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair