null

SMILES: CN1CCC(F)(CC1)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C

InChI Key: InChIKey=LKQQDFRBWPNRJF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C beta type (Homo sapiens (Human))	BDBM286377 (US11220518, Ex. No. L4 | US9518060, Example L4) Show SMILES CN1CCC(F)(CC1)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C Show InChI InChI=1S/C20H24F5N7O2/c1-18(2)13-11(9-32(18)16(33)19(22)4-6-31(3)7-5-19)14(30-29-13)27-15-12(21)8-26-17(28-15)34-10-20(23,24)25/h8H,4-7,9-10H2,1-3H3,(H2,26,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286377 (US11220518, Ex. No. L4 | US9518060, Example L4) Show SMILES CN1CCC(F)(CC1)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C Show InChI InChI=1S/C20H24F5N7O2/c1-18(2)13-11(9-32(18)16(33)19(22)4-6-31(3)7-5-19)14(30-29-13)27-15-12(21)8-26-17(28-15)34-10-20(23,24)25/h8H,4-7,9-10H2,1-3H3,(H2,26,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.71	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair