BDBM286385 US9518060, Example N2::US9518060, Example N3

SMILES: COCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1

InChI Key: InChIKey=QJAQNXAHOIPYAQ-LSLKUGRBSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PTK2B protein tyrosine kinase 2 beta (PTK2B) (Homo sapiens (Human))	BDBM286385 (US9518060, Example N2 | US9518060, Example N3) Show SMILES COCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C22H33FN8O3/c1-13-9-29(4)14(6-7-32)10-30(13)21(33)31-11-15-18(22(31,2)3)27-28-19(15)26-20-16(23)8-24-17(25-20)12-34-5/h8,13-14,32H,6-7,9-12H2,1-5H3,(H2,24,25,26,27,28)/t13-,14?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B) (Homo sapiens (Human))	BDBM286385 (US9518060, Example N2 | US9518060, Example N3) Show SMILES COCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C22H33FN8O3/c1-13-9-29(4)14(6-7-32)10-30(13)21(33)31-11-15-18(22(31,2)3)27-28-19(15)26-20-16(23)8-24-17(25-20)12-34-5/h8,13-14,32H,6-7,9-12H2,1-5H3,(H2,24,25,26,27,28)/t13-,14?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15.6	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair