BDBM286431 US9518064, Example 47

SMILES: COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3cnc(OC)nc3)cc(OC)cc2o1

InChI Key: InChIKey=HCSXISDLOQNVNM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 4 (PAR4) (Homo sapiens (Human))	BDBM286431 (US9518064, Example 47) Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3cnc(OC)nc3)cc(OC)cc2o1 Show InChI InChI=1S/C26H21N5O5S/c1-32-18-8-21(35-14-15-5-4-6-16(7-15)17-11-27-24(33-2)28-12-17)19-10-23(36-22(19)9-18)20-13-31-25(29-20)37-26(30-31)34-3/h4-13H,14H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company; Universite De Montreal US Patent					Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...				US Patent US9518064 (2016) BindingDB Entry DOI: 10.7270/Q2TT4SZX
					More data for this Ligand-Target Pair